Omadacycline
A tetracycline-class antibiotic used to treat community-acquired bacterial pneumonia and acute skin and skin structure infections caused by susceptible organisms. It is active against many multidrug-resistant bacteria including MRSA and atypical pathogens.
Molecular Weight
556.6000 g/mol
LogP
3.00
TPSA
177.00 Ų
Lipinski RO5
Fail
Therapeutic Areas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Structure
Cite this structure
Embed this structure
SMILES
CN(C)c1cc(CNCC(C)(C)C)c(O)c2c1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C1C2=O
InChI
InChI=1S/C29H40N4O7/c1-28(2,3)12-31-11-14-10-17(32(4)5)15-8-13-9-16-21(33(6)7)24(36)20(27(30)39)26(38)29(16,40)25(37)18(13)23(35)19(15)22(14)34/h10,13,16,21,31,34,36-37,40H,8-9,11-12H2,1-7H3,(H2,30,39)/t13-,16-,21-,29-/m0/s1
Molecular Formula
C29H40N4O7
HBD / HBA
6 / 10
Rotatable Bonds
7
Heavy Atoms
40
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
A tetracycline-class antibiotic used to treat community-acquired bacterial pneumonia and acute skin and skin structure infections caused by susceptible organisms. It is active against many multidrug-resistant bacteria including MRSA and atypical pathogens.
Yes, Omadacycline is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1689772. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 54697325. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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