Oxyphenbutazone
A nonsteroidal anti-inflammatory drug (NSAID) derived from phenylbutazone, used to treat pain and inflammation in conditions such as arthritis and gout. It has been largely withdrawn from many markets due to serious bone marrow toxicity.
Molecular Weight
324.4000 g/mol
LogP
2.70
TPSA
60.90 Ų
Lipinski RO5
Pass
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Structure
Cite this structure
Embed this structure
SMILES
CCCCC1C(=O)N(c2ccccc2)N(c2ccc(O)cc2)C1=O.O
InChI
InChI=1S/C19H20N2O3.H2O/c1-2-3-9-17-18(23)20(14-7-5-4-6-8-14)21(19(17)24)15-10-12-16(22)13-11-15;/h4-8,10-13,17,22H,2-3,9H2,1H3;1H2
Molecular Formula
C19H20N2O3
HBD / HBA
1 / 3
Rotatable Bonds
5
Heavy Atoms
24
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
A nonsteroidal anti-inflammatory drug (NSAID) derived from phenylbutazone, used to treat pain and inflammation in conditions such as arthritis and gout. It has been largely withdrawn from many markets due to serious bone marrow toxicity.
Yes, Oxyphenbutazone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989676. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 4641. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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