Pemetrexed Disodium Hemipentahydrate

CHEMBL6068335 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

1032.8 g/mol

LogP

—

Phase

4

A disodium hemipentahydrate form of pemetrexed with the same therapeutic properties. This chemotherapy drug stops cancer cells from making DNA and RNA, used primarily for lung cancer and mesothelioma.

Molecular Weight

1032.8000 g/mol

TPSA

390.00 Å²

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

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SMILES

Nc1nc2[nH]cc(CCc3ccc(C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-])cc3)c2c(=O)[nH]1.Nc1nc2[nH]cc(CCc3ccc(C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-])cc3)c2c(=O)[nH]1.O.O.O.O.O.[Na+].[Na+].[Na+].[Na+]

InChI

InChI=1S/2C20H21N5O6.4Na.5H2O/c2*21-20-24-16-15(18(29)25-20)12(9-22-16)6-3-10-1-4-11(5-2-10)17(28)23-13(19(30)31)7-8-14(26)27;;;;;;;;;/h2*1-2,4-5,9,13H,3,6-8H2,(H,23,28)(H,26,27)(H,30,31)(H4,21,22,24,25,29);;;;;5*1H2/q;;4*+1;;;;;/p-4/t2*13-;;;;;;;;;/m00........./s1

Molecular Formula

C40H48N10Na4O17

HBD / HBA

13 / 19

Rotatable Bonds

14

Heavy Atoms

71

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

A disodium hemipentahydrate form of pemetrexed with the same therapeutic properties. This chemotherapy drug stops cancer cells from making DNA and RNA, used primarily for lung cancer and mesothelioma.

Yes, Pemetrexed Disodium Hemipentahydrate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL6068335. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 135564527. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Quick Data

Formula: C40H48N10Na4O17

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.