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Pentetate Indium Disodium In 111

CHEMBL2107480 Phase 4 Approved Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
545.2 g/mol
LogP
—
Phase
4

A radioactive imaging agent in which indium-111 is chelated by DTPA, used in nuclear medicine to image cerebrospinal fluid spaces (cisternography) and evaluate CSF leaks or hydrocephalus. It is instilled intrathecally and its distribution is tracked by gamma camera imaging.

Molecular Weight

545.1900 g/mol

TPSA

210.00 Ų

Mechanism of Action

Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanism

Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.

SMILES

C(CN(CC(=O)[O-])CC(=O)[O-])N(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Na+].[Na+].[111In+3]

InChI

InChI=1S/C14H23N3O10.In.2Na/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;;;/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);;;/q;+3;2*+1/p-5/i;1-4;;

Molecular Formula

C14H18InN3Na2O10

HBD / HBA

- / 13

Rotatable Bonds

11

Heavy Atoms

30

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

A radioactive imaging agent in which indium-111 is chelated by DTPA, used in nuclear medicine to image cerebrospinal fluid spaces (cisternography) and evaluate CSF leaks or hydrocephalus. It is instilled intrathecally and its distribution is tracked by gamma camera imaging.

Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.

Yes, Pentetate Indium Disodium In 111 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2107480. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 23724985. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.