Perflubron
A perfluorocarbon liquid used as a partial liquid ventilation agent in premature infants with severe respiratory distress syndrome, and investigated as an oxygen-carrying blood substitute. It dissolves large quantities of oxygen and carbon dioxide, allowing gas exchange in fluid-filled lungs.
Molecular Weight
498.9600 g/mol
LogP
6.90
TPSA
0.00 Ų
Lipinski RO5
Fail
Therapeutic Areas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Structure
Cite this structure
Embed this structure
SMILES
FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Br
InChI
InChI=1S/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26
Molecular Formula
C8BrF17
HBD / HBA
- / 17
Rotatable Bonds
6
Heavy Atoms
26
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
A perfluorocarbon liquid used as a partial liquid ventilation agent in premature infants with severe respiratory distress syndrome, and investigated as an oxygen-carrying blood substitute. It dissolves large quantities of oxygen and carbon dioxide, allowing gas exchange in fluid-filled lungs.
Yes, Perflubron is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200866. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 9873. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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