Phenobarbital

CHEMBL40 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

232.2 g/mol

LogP

1.5

Phase

4

A long-acting medication used to control seizures in epilepsy and can also be used to treat anxiety or as a sedative before surgery. It works by calming overactive electrical signals in the brain that cause seizures.

Molecular Weight

232.2300 g/mol

LogP

1.50

TPSA

75.30 Å²

Lipinski RO5

Pass

Therapeutic Areas

Chronic Pain Epilepsy Generalized Anxiety Disorder Glaucoma Leukemia Lymphoma Malaria Multiple Sclerosis Pain Management Schizophrenia Stroke

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

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SMILES

CCC1(c2ccccc2)C(=O)NC(=O)NC1=O

InChI

InChI=1S/C12H12N2O3/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16/h3-7H,2H2,1H3,(H2,13,14,15,16,17)

Molecular Formula

C12H12N2O3

HBD / HBA

2 / 3

Rotatable Bonds

2

Heavy Atoms

17

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

A long-acting medication used to control seizures in epilepsy and can also be used to treat anxiety or as a sedative before surgery. It works by calming overactive electrical signals in the brain that cause seizures.

Yes, Phenobarbital is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL40. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4763. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Quick Data

Formula: C12H12N2O3
Synonyms: 8

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.