Phenylpropanolamine

CHEMBL61006 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

151.2 g/mol

LogP

0.8

Phase

4

A sympathomimetic drug previously used as a decongestant and appetite suppressant, though it has been largely withdrawn from the market in many countries due to an increased risk of hemorrhagic stroke. It may still appear in some veterinary or international formulations.

Molecular Weight

151.2100 g/mol

LogP

0.80

TPSA

46.30 Å²

Lipinski RO5

Pass

Therapeutic Areas

Asthma Atrial Fibrillation Benign Prostatic Hyperplasia Cardiovascular Disease Chronic Obstructive Pulmonary Disease Chronic Pain Heart Failure Hypertension Inflammatory Bowel Disease Leukemia Lymphoma Obesity Pain Management Psoriasis Rheumatoid Arthritis Schizophrenia Systemic Lupus Erythematosus Type 2 Diabetes

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

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SMILES

CC(N)C(O)c1ccccc1

InChI

InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3

Molecular Formula

C9H13NO

HBD / HBA

2 / 2

Rotatable Bonds

2

Heavy Atoms

11

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

A sympathomimetic drug previously used as a decongestant and appetite suppressant, though it has been largely withdrawn from the market in many countries due to an increased risk of hemorrhagic stroke. It may still appear in some veterinary or international formulations.

Yes, Phenylpropanolamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL61006. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 10297. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Quick Data

Formula: C9H13NO
Synonyms: 5

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.