Plazomicin

CHEMBL1650559 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

592.7 g/mol

LogP

-6.2

Phase

4

A newer aminoglycoside antibiotic designed to treat serious, difficult-to-treat bacterial infections including those caused by antibiotic-resistant bacteria such as carbapenem-resistant Enterobacteriaceae. It is given intravenously in hospital settings for complicated urinary tract and bloodstream infections.

Molecular Weight

592.7000 g/mol

LogP

-6.20

TPSA

269.00 Å²

Lipinski RO5

Fail

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

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SMILES

CN[C@@H]1[C@@H](O)[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3OC(CNCCO)=CC[C@H]3N)[C@@H](N)C[C@H]2NC(=O)[C@@H](O)CCN)OC[C@]1(C)O

InChI

InChI=1S/C25H48N6O10/c1-25(37)11-38-24(18(35)21(25)29-2)41-20-15(31-22(36)16(33)5-6-26)9-14(28)19(17(20)34)40-23-13(27)4-3-12(39-23)10-30-7-8-32/h3,13-21,23-24,29-30,32-35,37H,4-11,26-28H2,1-2H3,(H,31,36)/t13-,14+,15-,16+,17+,18-,19-,20+,21-,23-,24-,25+/m1/s1

Molecular Formula

C25H48N6O10

HBD / HBA

11 / 15

Rotatable Bonds

13

Heavy Atoms

41

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

A newer aminoglycoside antibiotic designed to treat serious, difficult-to-treat bacterial infections including those caused by antibiotic-resistant bacteria such as carbapenem-resistant Enterobacteriaceae. It is given intravenously in hospital settings for complicated urinary tract and bloodstream infections.

Yes, Plazomicin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1650559. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 42613186. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Quick Data

Formula: C25H48N6O10
Synonyms: 1

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.