Potassium Oxybate

CHEMBL4594395 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

142.2 g/mol

LogP

—

Phase

4

Potassium oxybate is the potassium salt form of gamma-hydroxybutyrate (GHB), a naturally occurring CNS depressant that acts on GABA-B receptors and specific GHB receptors in the brain to promote slow-wave sleep and reduce daytime sleepiness and cataplexy. It is used as an alternative formulation of sodium oxybate for the treatment of narcolepsy, particularly to reduce the sodium burden in patients with hypertension or sodium-restricted diets.

Molecular Weight

142.1900 g/mol

TPSA

60.40 Å²

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

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SMILES

O=C([O-])CCCO.[K+]

InChI

InChI=1S/C4H8O3.K/c5-3-1-2-4(6)7;/h5H,1-3H2,(H,6,7);/q;+1/p-1

Molecular Formula

C4H7KO3

HBD / HBA

1 / 3

Rotatable Bonds

3

Heavy Atoms

8

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

Potassium oxybate is the potassium salt form of gamma-hydroxybutyrate (GHB), a naturally occurring CNS depressant that acts on GABA-B receptors and specific GHB receptors in the brain to promote slow-wave sleep and reduce daytime sleepiness and cataplexy. It is used as an alternative formulation of sodium oxybate for the treatment of narcolepsy, particularly to reduce the sodium burden in patients with hypertension or sodium-restricted diets.

Yes, Potassium Oxybate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4594395. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 23689651. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Quick Data

Formula: C4H7KO3
Synonyms: 1

External Links

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.