Primaquine
An antiparasitic medication used to treat and prevent certain types of malaria, particularly to eliminate the dormant liver stages of Plasmodium vivax and Plasmodium ovale that can cause the infection to relapse weeks or months later. Before taking it, patients must be tested for a genetic enzyme deficiency (G6PD) that can cause serious blood problems.
Molecular Weight
259.3500 g/mol
LogP
2.20
TPSA
60.20 Ų
Lipinski RO5
Pass
Therapeutic Areas
Mechanism of Action
Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.
2D Structure
Cite this structure
Embed this structure
SMILES
COc1cc(NC(C)CCCN)c2ncccc2c1
InChI
InChI=1S/C15H21N3O/c1-11(5-3-7-16)18-14-10-13(19-2)9-12-6-4-8-17-15(12)14/h4,6,8-11,18H,3,5,7,16H2,1-2H3
Molecular Formula
C15H21N3O
HBD / HBA
2 / 4
Rotatable Bonds
6
Heavy Atoms
19
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
An antiparasitic medication used to treat and prevent certain types of malaria, particularly to eliminate the dormant liver stages of Plasmodium vivax and Plasmodium ovale that can cause the infection to relapse weeks or months later. Before taking it, patients must be tested for a genetic enzyme deficiency (G6PD) that can cause serious blood problems.
Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.
Yes, Primaquine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL506. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 4908. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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