Progesterone
A natural female hormone used in hormone replacement therapy, to support early pregnancy, and to treat conditions such as irregular menstrual periods, endometriosis, and abnormal uterine bleeding. It plays a key role in regulating the menstrual cycle and maintaining pregnancy.
Molecular Weight
314.5000 g/mol
LogP
3.90
TPSA
34.10 Ų
Lipinski RO5
Pass
Therapeutic Areas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Structure
Cite this structure
Embed this structure
SMILES
CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI
InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
Molecular Formula
C21H30O2
HBD / HBA
- / 2
Rotatable Bonds
1
Heavy Atoms
23
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
A natural female hormone used in hormone replacement therapy, to support early pregnancy, and to treat conditions such as irregular menstrual periods, endometriosis, and abnormal uterine bleeding. It plays a key role in regulating the menstrual cycle and maintaining pregnancy.
Yes, Progesterone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL103. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5994. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="progesterone"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/progesterone/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/progesterone/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/progesterone/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="progesterone"></drugfyi-drug>