Propafenone Hydrochloride

CHEMBL1201063 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

377.9 g/mol

LogP

—

Phase

4

A hydrochloride salt form of propafenone with the same therapeutic properties. Used to treat certain serious abnormal heart rhythms, including atrial fibrillation and other supraventricular arrhythmias, by slowing electrical conduction in the heart to restore and maintain a normal rhythm.

Molecular Weight

377.9000 g/mol

TPSA

58.60 Å²

Therapeutic Areas

Atrial Fibrillation

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

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SMILES

CCCNCC(O)COc1ccccc1C(=O)CCc1ccccc1.Cl

InChI

InChI=1S/C21H27NO3.ClH/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17;/h3-11,18,22-23H,2,12-16H2,1H3;1H

Molecular Formula

C21H28ClNO3

HBD / HBA

3 / 4

Rotatable Bonds

11

Heavy Atoms

26

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

A hydrochloride salt form of propafenone with the same therapeutic properties. Used to treat certain serious abnormal heart rhythms, including atrial fibrillation and other supraventricular arrhythmias, by slowing electrical conduction in the heart to restore and maintain a normal rhythm.

Yes, Propafenone Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201063. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 36708. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Quick Data

Formula: C21H28ClNO3
Synonyms: 1

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.