Propyphenazone
Propyphenazone is a pyrazolone-class non-steroidal anti-inflammatory and analgesic agent that inhibits cyclooxygenase enzymes to reduce prostaglandin synthesis, producing analgesic, antipyretic, and anti-inflammatory effects. It is used in combination with caffeine and other analgesics for the treatment of tension headache, migraine, and mild to moderate pain.
Molecular Weight
230.3100 g/mol
LogP
1.70
TPSA
23.60 Ų
Lipinski RO5
Pass
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Structure
Cite this structure
Embed this structure
SMILES
Cc1c(C(C)C)c(=O)n(-c2ccccc2)n1C
InChI
InChI=1S/C14H18N2O/c1-10(2)13-11(3)15(4)16(14(13)17)12-8-6-5-7-9-12/h5-10H,1-4H3
Molecular Formula
C14H18N2O
HBD / HBA
- / 2
Rotatable Bonds
2
Heavy Atoms
17
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
Propyphenazone is a pyrazolone-class non-steroidal anti-inflammatory and analgesic agent that inhibits cyclooxygenase enzymes to reduce prostaglandin synthesis, producing analgesic, antipyretic, and anti-inflammatory effects. It is used in combination with caffeine and other analgesics for the treatment of tension headache, migraine, and mild to moderate pain.
Yes, Propyphenazone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL28318. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3778. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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