Sevoflurane
Sevoflurane is a halogenated ether inhalational anesthetic that produces dose-dependent CNS depression through multiple mechanisms including potentiation of GABA-A receptors, inhibition of NMDA receptors, and modulation of two-pore domain potassium channels, used for induction and maintenance of general anesthesia. Its low blood-gas partition coefficient enables rapid onset and offset of anesthesia with smooth induction and recovery properties. It is widely used for outpatient procedures due to its favorable pharmacokinetic profile.
Molecular Weight
200.0500 g/mol
LogP
2.80
TPSA
9.20 Ų
Lipinski RO5
Pass
Therapeutic Areas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Structure
Cite this structure
Embed this structure
SMILES
FCOC(C(F)(F)F)C(F)(F)F
InChI
InChI=1S/C4H3F7O/c5-1-12-2(3(6,7)8)4(9,10)11/h2H,1H2
Molecular Formula
C4H3F7O
HBD / HBA
- / 8
Rotatable Bonds
2
Heavy Atoms
12
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
Sevoflurane is a halogenated ether inhalational anesthetic that produces dose-dependent CNS depression through multiple mechanisms including potentiation of GABA-A receptors, inhibition of NMDA receptors, and modulation of two-pore domain potassium channels, used for induction and maintenance of general anesthesia. Its low blood-gas partition coefficient enables rapid onset and offset of anesthesia with smooth induction and recovery properties. It is widely used for outpatient procedures due to its favorable pharmacokinetic profile.
Yes, Sevoflurane is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200694. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5206. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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