Sibutramine Hydrochloride

CHEMBL3989830 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

316.3 g/mol

LogP

—

Phase

4

Sibutramine hydrochloride is the hydrochloride salt form of sibutramine, a serotonin-norepinephrine reuptake inhibitor formerly used for obesity management that was withdrawn due to cardiovascular safety concerns. See sibutramine for complete pharmacological details.

Molecular Weight

316.3000 g/mol

TPSA

3.20 Å²

Therapeutic Areas

Asthma Bipolar Disorder Cardiovascular Disease Hypertension Obesity Schizophrenia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

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SMILES

CC(C)CC(N(C)C)C1(c2ccc(Cl)cc2)CCC1.Cl.O

InChI

InChI=1S/C17H26ClN.ClH.H2O/c1-13(2)12-16(19(3)4)17(10-5-11-17)14-6-8-15(18)9-7-14;;/h6-9,13,16H,5,10-12H2,1-4H3;1H;1H2

Molecular Formula

C17H27Cl2N

HBD / HBA

1 / 1

Rotatable Bonds

5

Heavy Atoms

20

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

Sibutramine hydrochloride is the hydrochloride salt form of sibutramine, a serotonin-norepinephrine reuptake inhibitor formerly used for obesity management that was withdrawn due to cardiovascular safety concerns. See sibutramine for complete pharmacological details.

Yes, Sibutramine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989830. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 64764. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Quick Data

Formula: C17H27Cl2N

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.