Sodium Iodide I 131
Sodium iodide I-131 is a beta and gamma-emitting radioactive iodine used therapeutically for ablation of normal thyroid remnants post-thyroidectomy, treatment of differentiated thyroid cancer metastases, and hyperthyroidism, as well as diagnostically for thyroid cancer staging. The thyroid's avid uptake of iodide concentrates the radioactive iodine-131, where beta emissions deliver targeted radiation to destroy thyroid tissue. It is a cornerstone of differentiated thyroid cancer management following surgery.
Molecular Weight
153.8959 g/mol
TPSA
0.00 Ų
Therapeutic Areas
Mechanism of Action
Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.
2D Structure
Cite this structure
Embed this structure
SMILES
[131I-].[Na+]
InChI
InChI=1S/HI.Na/h1H;/q;+1/p-1/i1+4;
Molecular Formula
INa
HBD / HBA
- / 1
Rotatable Bonds
0
Heavy Atoms
2
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
Sodium iodide I-131 is a beta and gamma-emitting radioactive iodine used therapeutically for ablation of normal thyroid remnants post-thyroidectomy, treatment of differentiated thyroid cancer metastases, and hyperthyroidism, as well as diagnostically for thyroid cancer staging. The thyroid's avid uptake of iodide concentrates the radioactive iodine-131, where beta emissions deliver targeted radiation to destroy thyroid tissue. It is a cornerstone of differentiated thyroid cancer management following surgery.
Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.
Yes, Sodium Iodide I 131 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201084. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 71368. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="sodium-iodide-i-131"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/sodium-iodide-i-131/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/sodium-iodide-i-131/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/sodium-iodide-i-131/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="sodium-iodide-i-131"></drugfyi-drug>