Sparfloxacin
A fluoroquinolone antibiotic that kills bacteria by interfering with their DNA replication machinery, used to treat respiratory and other serious infections. Its use has become limited due to photosensitivity reactions and the potential to prolong the QT interval in the heart, raising arrhythmia concerns.
Molecular Weight
392.4000 g/mol
LogP
0.10
TPSA
98.90 Ų
Lipinski RO5
Pass
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Structure
Cite this structure
Embed this structure
SMILES
C[C@@H]1CN(c2c(F)c(N)c3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C[C@H](C)N1
InChI
InChI=1S/C19H22F2N4O3/c1-8-5-24(6-9(2)23-8)17-13(20)15(22)12-16(14(17)21)25(10-3-4-10)7-11(18(12)26)19(27)28/h7-10,23H,3-6,22H2,1-2H3,(H,27,28)/t8-,9+
Molecular Formula
C19H22F2N4O3
HBD / HBA
3 / 9
Rotatable Bonds
3
Heavy Atoms
28
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
A fluoroquinolone antibiotic that kills bacteria by interfering with their DNA replication machinery, used to treat respiratory and other serious infections. Its use has become limited due to photosensitivity reactions and the potential to prolong the QT interval in the heart, raising arrhythmia concerns.
Yes, Sparfloxacin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL850. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 60464. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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