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Sulbactam

CHEMBL403 Phase 4 Approved Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
233.2 g/mol
LogP
-1.0
Phase
4

A beta-lactamase inhibitor that protects penicillin-type antibiotics from being destroyed by bacterial enzymes, thereby restoring their effectiveness against resistant bacteria. It is used in combination with ampicillin to treat intra-abdominal infections, gynecological infections, and skin infections caused by resistant organisms.

Molecular Weight

233.2400 g/mol

LogP

-1.00

TPSA

100.00 Ų

Lipinski RO5

Pass

Therapeutic Areas

Breast Cancer Infectious Disease

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CC1(C)[C@H](C(=O)O)N2C(=O)C[C@H]2S1(=O)=O

                

                

                
                

                    
InChI

                    
InChI=1S/C8H11NO5S/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14/h5-6H,3H2,1-2H3,(H,11,12)/t5-,6+/m1/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C8H11NO5S

                    

                    
                    

                        
HBD / HBA

                        
1 / 5

                    

                    
                    

                        
Rotatable Bonds

                        
1

                    

                    
                    
                    

                        
Heavy Atoms

                        
15

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Frequently Asked Questions

                

                    
                    

                        
                        

                            
A beta-lactamase inhibitor that protects penicillin-type antibiotics from being destroyed by bacterial enzymes, thereby restoring their effectiveness against resistant bacteria. It is used in combination with ampicillin to treat intra-abdominal infections, gynecological infections, and skin infections caused by resistant organisms.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Sulbactam is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL403.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 130313.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Medical Disclaimer

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.