Sulindac

CHEMBL15770 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

356.4 g/mol

LogP

3.4

Phase

4

A non-steroidal anti-inflammatory drug that reduces pain and inflammation by inhibiting prostaglandin production, used for arthritis, acute gout, and other musculoskeletal pain conditions. Research has also explored its potential to inhibit the growth of colon and other cancer cells through additional mechanisms beyond COX inhibition.

Molecular Weight

356.4000 g/mol

LogP

3.40

TPSA

73.60 Å²

Lipinski RO5

Pass

Therapeutic Areas

Bladder Cancer Breast Cancer Chronic Pain Colorectal Cancer Glaucoma Hypertension Leukemia Melanoma Non-Small Cell Lung Cancer Ovarian Cancer Pain Management Pancreatic Cancer Prostate Cancer Thyroid Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

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SMILES

CC1=C(CC(=O)O)c2cc(F)ccc2/C1=C\c1ccc([S+](C)[O-])cc1

InChI

InChI=1S/C20H17FO3S/c1-12-17(9-13-3-6-15(7-4-13)25(2)24)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9-

Molecular Formula

C20H17FO3S

HBD / HBA

1 / 5

Rotatable Bonds

4

Heavy Atoms

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

A non-steroidal anti-inflammatory drug that reduces pain and inflammation by inhibiting prostaglandin production, used for arthritis, acute gout, and other musculoskeletal pain conditions. Research has also explored its potential to inhibit the growth of colon and other cancer cells through additional mechanisms beyond COX inhibition.

Yes, Sulindac is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL15770. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 1548887. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Quick Data

Formula: C20H17FO3S

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.