Tabelecleucel
Tabelecleucel is an allogeneic (off-the-shelf) Epstein-Barr virus (EBV)-specific cytotoxic T lymphocyte (CTL) cell therapy used for the treatment of EBV-positive post-transplant lymphoproliferative disease (EBV+ PTLD) in patients who have failed rituximab or rituximab plus chemotherapy. The EBV-specific T cells are manufactured from healthy HLA-typed donors and selected for HLA compatibility to ensure recognition of EBV-infected lymphoma cells expressing viral antigens. It provides adoptive cellular immunity against EBV-driven malignancy in immunocompromised transplant recipients.
Therapeutic Areas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
HBD / HBA
- / -
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
Tabelecleucel is an allogeneic (off-the-shelf) Epstein-Barr virus (EBV)-specific cytotoxic T lymphocyte (CTL) cell therapy used for the treatment of EBV-positive post-transplant lymphoproliferative disease (EBV+ PTLD) in patients who have failed rituximab or rituximab plus chemotherapy. The EBV-specific T cells are manufactured from healthy HLA-typed donors and selected for HLA compatibility to ensure recognition of EBV-infected lymphoma cells expressing viral antigens. It provides adoptive cellular immunity against EBV-driven malignancy in immunocompromised transplant recipients.
Yes, Tabelecleucel is an approved drug. It has reached clinical phase 4. It is classified as a Cell.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3990008. Open-access bioactivity database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.
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