Telithromycin

CHEMBL1136 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

812.0 g/mol

LogP

4.2

Phase

4

This antibiotic belongs to the ketolide class and was used to treat community-acquired pneumonia caused by susceptible bacteria. It works by blocking bacterial protein production. Due to serious liver toxicity concerns, its use is now very restricted.

Molecular Weight

812.0000 g/mol

LogP

4.20

TPSA

172.00 Å²

Lipinski RO5

Fail

Therapeutic Areas

Asthma

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

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SMILES

CC[C@H]1OC(=O)[C@H](C)C(=O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(OC)C[C@@H](C)C(=O)[C@H](C)[C@H]2N(CCCCn3cnc(-c4cccnc4)c3)C(=O)O[C@]12C

InChI

InChI=1S/C43H65N5O10/c1-12-33-43(8)37(48(41(53)58-43)19-14-13-18-47-23-31(45-24-47)30-16-15-17-44-22-30)27(4)34(49)25(2)21-42(7,54-11)38(28(5)35(50)29(6)39(52)56-33)57-40-36(51)32(46(9)10)20-26(3)55-40/h15-17,22-29,32-33,36-38,40,51H,12-14,18-21H2,1-11H3/t25-,26-,27+,28+,29-,32+,33-,36-,37-,38-,40+,42-,43-/m1/s1

Molecular Formula

C43H65N5O10

HBD / HBA

1 / 13

Rotatable Bonds

11

Heavy Atoms

58

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

This antibiotic belongs to the ketolide class and was used to treat community-acquired pneumonia caused by susceptible bacteria. It works by blocking bacterial protein production. Due to serious liver toxicity concerns, its use is now very restricted.

Yes, Telithromycin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1136. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 3002190. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Quick Data

Formula: C43H65N5O10
Synonyms: 1

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.