Treprostinil Sodium

CHEMBL561157 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

412.5 g/mol

LogP

—

Phase

4

Treprostinil sodium is the sodium salt form of treprostinil, a synthetic prostacyclin analog used for pulmonary arterial hypertension via continuous subcutaneous or intravenous infusion and inhaled delivery. See treprostinil for complete pharmacological details. This salt formulation is used in sterile injectable preparations for continuous infusion therapy in COPD-associated pulmonary hypertension and PAH.

Molecular Weight

412.5000 g/mol

TPSA

89.80 Å²

Therapeutic Areas

Chronic Obstructive Pulmonary Disease Hypertension

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

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SMILES

CCCCC[C@H](O)CC[C@@H]1[C@H]2Cc3cccc(OCC(=O)[O-])c3C[C@H]2C[C@H]1O.[Na+]

InChI

InChI=1S/C23H34O5.Na/c1-2-3-4-7-17(24)9-10-18-19-11-15-6-5-8-22(28-14-23(26)27)20(15)12-16(19)13-21(18)25;/h5-6,8,16-19,21,24-25H,2-4,7,9-14H2,1H3,(H,26,27);/q;+1/p-1/t16-,17-,18+,19-,21+;/m0./s1

Molecular Formula

C23H33NaO5

HBD / HBA

2 / 5

Rotatable Bonds

10

Heavy Atoms

29

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

Treprostinil sodium is the sodium salt form of treprostinil, a synthetic prostacyclin analog used for pulmonary arterial hypertension via continuous subcutaneous or intravenous infusion and inhaled delivery. See treprostinil for complete pharmacological details. This salt formulation is used in sterile injectable preparations for continuous infusion therapy in COPD-associated pulmonary hypertension and PAH.

Yes, Treprostinil Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL561157. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 23663413. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Quick Data

Formula: C23H33NaO5

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.