Trifluoperazine Hydrochloride
Trifluoperazine hydrochloride is the hydrochloride salt form of trifluoperazine, a high-potency phenothiazine antipsychotic dopamine D2 receptor antagonist. See trifluoperazine for complete pharmacological details. This salt formulation provides water-soluble form for oral tablet, liquid, and injectable preparations in schizophrenia and anxiety management.
Molecular Weight
480.4000 g/mol
TPSA
35.00 Ų
Mechanism of Action
Competitively binds to its target receptor without activating it, blocking the natural ligand from binding and preventing receptor-mediated signaling.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Competitively binds to its target receptor without activating it, blocking the natural ligand from binding and preventing receptor-mediated signaling.
2D Structure
Cite this structure
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SMILES
CN1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1.Cl.Cl
InChI
InChI=1S/C21H24F3N3S.2ClH/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24;;/h2-3,5-8,15H,4,9-14H2,1H3;2*1H
Molecular Formula
C21H26Cl2F3N3S
HBD / HBA
2 / 7
Rotatable Bonds
4
Heavy Atoms
30
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
Trifluoperazine hydrochloride is the hydrochloride salt form of trifluoperazine, a high-potency phenothiazine antipsychotic dopamine D2 receptor antagonist. See trifluoperazine for complete pharmacological details. This salt formulation provides water-soluble form for oral tablet, liquid, and injectable preparations in schizophrenia and anxiety management.
Competitively binds to its target receptor without activating it, blocking the natural ligand from binding and preventing receptor-mediated signaling.
Yes, Trifluoperazine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1257040. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 66064. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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