Trypan Blue

CHEMBL1640 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

960.8 g/mol

LogP

—

Phase

4

Trypan blue is a diazo dye used in ophthalmic surgery as a vital stain to visualize and stain the anterior lens capsule and epiretinal membranes during cataract and vitreoretinal surgery, facilitating precise surgical dissection. It selectively stains dead or compromised cells (used in cell viability assays) and is applied intracamerally or intravitreally during ocular procedures. Its use improves surgical precision in glaucoma, cataract, and retinal surgeries.

Molecular Weight

960.8000 g/mol

TPSA

404.00 Å²

Therapeutic Areas

Glaucoma

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

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SMILES

Cc1cc(-c2ccc(/N=N/c3c(S(=O)(=O)[O-])cc4cc(S(=O)(=O)[O-])cc(N)c4c3O)c(C)c2)ccc1/N=N/c1c(S(=O)(=O)[O-])cc2cc(S(=O)(=O)[O-])cc(N)c2c1O.[Na+].[Na+].[Na+].[Na+]

InChI

InChI=1S/C34H28N6O14S4.4Na/c1-15-7-17(3-5-25(15)37-39-31-27(57(49,50)51)11-19-9-21(55(43,44)45)13-23(35)29(19)33(31)41)18-4-6-26(16(2)8-18)38-40-32-28(58(52,53)54)12-20-10-22(56(46,47)48)14-24(36)30(20)34(32)42;;;;/h3-14,41-42H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);;;;/q;4*+1/p-4/b39-37+,40-38+;;;;

Molecular Formula

C34H24N6Na4O14S4

HBD / HBA

4 / 20

Rotatable Bonds

5

Heavy Atoms

62

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

Trypan blue is a diazo dye used in ophthalmic surgery as a vital stain to visualize and stain the anterior lens capsule and epiretinal membranes during cataract and vitreoretinal surgery, facilitating precise surgical dissection. It selectively stains dead or compromised cells (used in cell viability assays) and is applied intracamerally or intravitreally during ocular procedures. Its use improves surgical precision in glaucoma, cataract, and retinal surgeries.

Yes, Trypan Blue is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1640. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6296. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Quick Data

Formula: C34H24N6Na4O14S4
Synonyms: 2

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.