Vortioxetine

CHEMBL2104993 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

298.4 g/mol

LogP

4.2

Phase

4

This multimodal antidepressant is used to treat major depressive disorder and works by both blocking serotonin reuptake and modulating multiple serotonin receptor subtypes, which may offer benefits for mood and cognitive function. Unlike some antidepressants, it may improve concentration and memory alongside mood. Sexual side effects are generally less common than with typical SSRIs.

Molecular Weight

298.4000 g/mol

LogP

4.20

TPSA

40.60 Å²

Lipinski RO5

Pass

Therapeutic Areas

Bipolar Disorder Bladder Cancer Breast Cancer Cardiovascular Disease Colorectal Cancer Generalized Anxiety Disorder Major Depressive Disorder Non-Small Cell Lung Cancer Ovarian Cancer Pancreatic Cancer Prostate Cancer Schizophrenia Thyroid Cancer Type 2 Diabetes

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

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SMILES

Cc1ccc(Sc2ccccc2N2CCNCC2)c(C)c1

InChI

InChI=1S/C18H22N2S/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3

Molecular Formula

C18H22N2S

HBD / HBA

1 / 3

Rotatable Bonds

3

Heavy Atoms

21

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

This multimodal antidepressant is used to treat major depressive disorder and works by both blocking serotonin reuptake and modulating multiple serotonin receptor subtypes, which may offer benefits for mood and cognitive function. Unlike some antidepressants, it may improve concentration and memory alongside mood. Sexual side effects are generally less common than with typical SSRIs.

Yes, Vortioxetine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2104993. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 9966051. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Quick Data

Formula: C18H22N2S
Synonyms: 1

External Links

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.