Bleomycin
A mixture of anticancer glycopeptides that damages cancer cell DNA, used to treat certain lymphomas, testicular cancers, and squamous cell carcinomas. It is also used in procedures to prevent recurrent pleural effusions. A significant risk is pulmonary toxicity, which can cause permanent lung scarring.
Peso molecular
1415,6000 g/mol
LogP
-7,50
TPSA
685,00 Ų
Regla de cinco de Lipinski
No cumple
Áreas terapéuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estructura 2D
Cite this structure
Embed this structure
SMILES
CC1=C(N=C(N=C1N)[C@H](CC(=O)N)NC[C@@H](C(=O)N)N)C(=O)N[C@@H]([C@H](C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)N[C@H](C)[C@H]([C@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O
InChI
InChI=1S/C55H83N17O21S3/c1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6/h14,17-19,21-25,29-30,34-43,53-54,64,73-75,77-81H,7-13,15-16,56H2,1-6H3,(H13-,57,58,59,60,61,62,63,65,66,69,70,71,72,76,82,83,84,85,86,87,88)/p+1/t21-,22+,23+,24-,25-,29?,30?,34-,35-,36-,37?,38?,39?,40?,41-,42?,43?,53?,54?/m0/s1
Molecular Formula
C55H84N17O21S3+
HBD / HBA
20 / 31
Enlaces Rotables
36
Átomos Pesados
96
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A mixture of anticancer glycopeptides that damages cancer cell DNA, used to treat certain lymphomas, testicular cancers, and squamous cell carcinomas. It is also used in procedures to prevent recurrent pleural effusions. A significant risk is pulmonary toxicity, which can cause permanent lung scarring.
Yes, Bleomycin is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL6067492. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5360373. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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