Cangrelor
A short-acting intravenous antiplatelet drug that rapidly inhibits the P2Y12 receptor to prevent platelet aggregation during and after heart procedures such as percutaneous coronary intervention. Its very short half-life allows quick reversal of antiplatelet effects, which is useful when bridging to oral therapy. It is used in patients who have not been pre-treated with oral P2Y12 inhibitors.
Peso molecular
776,4000 g/mol
LogP
-1,00
TPSA
307,00 Ų
Regla de cinco de Lipinski
No cumple
Áreas terapéuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estructura 2D
Cite this structure
Embed this structure
SMILES
CSCCNc1nc(SCCC(F)(F)F)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)C(Cl)(Cl)P(=O)(O)O)[C@@H](O)[C@H]1O
InChI
InChI=1S/C17H25Cl2F3N5O12P3S2/c1-43-5-3-23-12-9-13(26-15(25-12)44-4-2-16(20,21)22)27(7-24-9)14-11(29)10(28)8(38-14)6-37-42(35,36)39-41(33,34)17(18,19)40(30,31)32/h7-8,10-11,14,28-29H,2-6H2,1H3,(H,33,34)(H,35,36)(H,23,25,26)(H2,30,31,32)/t8-,10-,11-,14-/m1/s1
Molecular Formula
C17H25Cl2F3N5O12P3S2
HBD / HBA
7 / 21
Enlaces Rotables
15
Átomos Pesados
44
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A short-acting intravenous antiplatelet drug that rapidly inhibits the P2Y12 receptor to prevent platelet aggregation during and after heart procedures such as percutaneous coronary intervention. Its very short half-life allows quick reversal of antiplatelet effects, which is useful when bridging to oral therapy. It is used in patients who have not been pre-treated with oral P2Y12 inhibitors.
Yes, Cangrelor is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL334966. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 9854012. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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