Edoxaban
A direct oral anticoagulant that inhibits factor Xa, a key protein in the blood clotting cascade, used to prevent stroke in patients with atrial fibrillation and to treat blood clots in veins. It does not require routine blood monitoring unlike older blood thinners.
Peso molecular
548,0530 g/mol
LogP
1,40
TPSA
165,00 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Clases de fármacos
Mecanismo de acción
Direct, selective inhibitor of Factor Xa preventing thrombin generation and clot formation.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Direct, selective inhibitor of Factor Xa preventing thrombin generation and clot formation.
Estructura 2D
Cite this structure
Embed this structure
SMILES
CN1CCc2nc(C(=O)N[C@@H]3C[C@@H](C(=O)N(C)C)CC[C@@H]3NC(=O)C(=O)Nc3ccc(Cl)cn3)sc2C1
InChI
InChI=1S/C24H30ClN7O4S/c1-31(2)24(36)13-4-6-15(27-20(33)21(34)30-19-7-5-14(25)11-26-19)17(10-13)28-22(35)23-29-16-8-9-32(3)12-18(16)37-23/h5,7,11,13,15,17H,4,6,8-10,12H2,1-3H3,(H,27,33)(H,28,35)(H,26,30,34)/t13-,15-,17+/m0/s1
Molecular Formula
C24H30ClN7O4S
HBD / HBA
3 / 8
Enlaces Rotables
5
Átomos Pesados
37
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A direct oral anticoagulant that inhibits factor Xa, a key protein in the blood clotting cascade, used to prevent stroke in patients with atrial fibrillation and to treat blood clots in veins. It does not require routine blood monitoring unlike older blood thinners.
Direct, selective inhibitor of Factor Xa preventing thrombin generation and clot formation.
Key pharmacokinetic parameters for Edoxaban: Half-life: 10-14 hours.
Yes, Edoxaban is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
Related Drugs
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1269025. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 10280735. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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