Fomepizole
This medication works by blocking the enzyme alcohol dehydrogenase, preventing the body from converting methanol or ethylene glycol into toxic metabolites that can cause blindness, kidney failure, and death. It is used as an antidote in emergency treatment of methanol and antifreeze poisoning.
Peso molecular
82,1000 g/mol
LogP
1,40
TPSA
28,70 Ų
Regla de cinco de Lipinski
Cumple
Mecanismo de acción
Counteracts the effects of a specific toxin or drug overdose through competitive antagonism, enhanced elimination, or direct chemical neutralization.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Counteracts the effects of a specific toxin or drug overdose through competitive antagonism, enhanced elimination, or direct chemical neutralization.
Estructura 2D
Cite this structure
Embed this structure
SMILES
Cc1cn[nH]c1
InChI
InChI=1S/C4H6N2/c1-4-2-5-6-3-4/h2-3H,1H3,(H,5,6)
Molecular Formula
C4H6N2
HBD / HBA
1 / 1
Enlaces Rotables
0
Átomos Pesados
6
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
This medication works by blocking the enzyme alcohol dehydrogenase, preventing the body from converting methanol or ethylene glycol into toxic metabolites that can cause blindness, kidney failure, and death. It is used as an antidote in emergency treatment of methanol and antifreeze poisoning.
Counteracts the effects of a specific toxin or drug overdose through competitive antagonism, enhanced elimination, or direct chemical neutralization.
Yes, Fomepizole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1308. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3406. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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