Hydroquinone
A topical skin-lightening agent used to treat hyperpigmentation conditions such as melasma, age spots, and post-inflammatory hyperpigmentation by inhibiting the enzyme tyrosinase, which is needed for melanin production in the skin. It has also been investigated for antioxidant and other biological properties in research contexts. Long-term or excessive use can paradoxically cause ochronosis, a darkening of the skin.
Peso molecular
110,1100 g/mol
LogP
0,60
TPSA
40,50 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Mecanismo de acción
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Estructura 2D
Cite this structure
Embed this structure
SMILES
Oc1ccc(O)cc1
InChI
InChI=1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H
Molecular Formula
C6H6O2
HBD / HBA
2 / 2
Enlaces Rotables
0
Átomos Pesados
8
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A topical skin-lightening agent used to treat hyperpigmentation conditions such as melasma, age spots, and post-inflammatory hyperpigmentation by inhibiting the enzyme tyrosinase, which is needed for melanin production in the skin. It has also been investigated for antioxidant and other biological properties in research contexts. Long-term or excessive use can paradoxically cause ochronosis, a darkening of the skin.
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Yes, Hydroquinone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL537. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 785. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="hydroquinone"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/hydroquinone/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/hydroquinone/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/hydroquinone/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="hydroquinone"></drugfyi-drug>