Ketorolac Tromethamine

CHEMBL1201124 Phase 4 Aprobado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

376.4 g/mol

LogP

—

Phase

4

The tromethamine salt form of ketorolac, a potent NSAID used for short-term treatment of moderate to severe acute pain. It is often used as an alternative to opioids for postoperative pain management.

Peso molecular

376,4000 g/mol

TPSA

146,00 Å²

Áreas terapéuticas

Cáncer de mama Cáncer de ovario Cáncer de páncreas Cáncer de pulmón de células no pequeñas Degeneración macular relacionada con la edad Diabetes tipo 2 Dolor crónico Glaucoma Gota Hipertensión Linfoma Manejo del dolor Migraña Trombosis venosa profunda / Embolia pulmonar

Mecanismo de acción

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mecanismo

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission …

Estructura 2D

SVG PNG

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SMILES

NC(CO)(CO)CO.O=C(c1ccccc1)c1ccc2n1CCC2C(=O)O

InChI

InChI=1S/C15H13NO3.C4H11NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13;5-4(1-6,2-7)3-8/h1-7,11H,8-9H2,(H,18,19);6-8H,1-3,5H2

Molecular Formula

C19H24N2O6

HBD / HBA

5 / 7

Enlaces Rotables

6

Átomos Pesados

27

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

The tromethamine salt form of ketorolac, a potent NSAID used for short-term treatment of moderate to severe acute pain. It is often used as an alternative to opioids for postoperative pain management.

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Yes, Ketorolac Tromethamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201124. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 84003. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Estructura

Datos Rápidos

Fórmula: C19H24N2O6
Sinónimos: 18

Enlaces externos

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Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.