Ketorolac Tromethamine

CHEMBL1201124 Phase 4 Đã phê duyệt Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

376.4 g/mol

LogP

—

Phase

4

The tromethamine salt form of ketorolac, a potent NSAID used for short-term treatment of moderate to severe acute pain. It is often used as an alternative to opioids for postoperative pain management.

Khối lượng phân tử

376,4000 g/mol

TPSA

146,00 Å²

Lĩnh vực điều trị

Ovarian Cancer Pancreatic Cancer Glaucoma Age-Related Macular Degeneration Pain Management Non-Small Cell Lung Cancer Migraine Deep Vein Thrombosis / Pulmonary Embolism Lymphoma Type 2 Diabetes Hypertension Breast Cancer Gout Chronic Pain

Cơ chế tác dụng

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission …

Cấu trúc 2D

SVG PNG

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SMILES

NC(CO)(CO)CO.O=C(c1ccccc1)c1ccc2n1CCC2C(=O)O

InChI

InChI=1S/C15H13NO3.C4H11NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13;5-4(1-6,2-7)3-8/h1-7,11H,8-9H2,(H,18,19);6-8H,1-3,5H2

Molecular Formula

C19H24N2O6

HBD / HBA

5 / 7

Liên kết có thể quay

6

Nguyên tử nặng

27

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Câu hỏi thường gặp

The tromethamine salt form of ketorolac, a potent NSAID used for short-term treatment of moderate to severe acute pain. It is often used as an alternative to opioids for postoperative pain management.

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Yes, Ketorolac Tromethamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201124. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 84003. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Cấu trúc

Dữ liệu nhanh

Công thức: C19H24N2O6
Tên đồng nghĩa: 18

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Tuyên bố miễn trách y tế

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.