Levofloxacin
A broad-spectrum fluoroquinolone antibiotic used to treat respiratory tract infections, urinary tract infections, skin infections, and certain cases of anthrax. It works by inhibiting bacterial DNA gyrase and topoisomerase IV enzymes.
Peso molecular
361,3680 g/mol
LogP
-0,40
TPSA
73,30 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Clases de fármacos
Mecanismo de acción
Fluoroquinolone antibiotic inhibiting bacterial DNA gyrase and topoisomerase IV.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Fluoroquinolone antibiotic inhibiting bacterial DNA gyrase and topoisomerase IV.
Estructura 2D
Cite this structure
Embed this structure
SMILES
C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23.C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23.O
InChI
InChI=1S/2C18H20FN3O4.H2O/c2*1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21;/h2*7-8,10H,3-6,9H2,1-2H3,(H,24,25);1H2/t2*10-;/m00./s1
Molecular Formula
C18H20FN3O4
HBD / HBA
1 / 8
Enlaces Rotables
2
Átomos Pesados
26
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A broad-spectrum fluoroquinolone antibiotic used to treat respiratory tract infections, urinary tract infections, skin infections, and certain cases of anthrax. It works by inhibiting bacterial DNA gyrase and topoisomerase IV enzymes.
Fluoroquinolone antibiotic inhibiting bacterial DNA gyrase and topoisomerase IV.
Key pharmacokinetic parameters for Levofloxacin: Half-life: 6-8 hours.
Yes, Levofloxacin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
Related Drugs
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL5315124. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 149096. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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