Loxoprofen
A prodrug NSAID that is converted to its active form in the body, used in Japan and other Asian countries to treat pain and inflammation from arthritis and musculoskeletal conditions. It may have a lower rate of gastrointestinal side effects than some other NSAIDs.
Peso molecular
246,3000 g/mol
LogP
2,40
TPSA
54,40 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Mecanismo de acción
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Estructura 2D
Cite this structure
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SMILES
CC(C(=O)O)c1ccc(CC2CCCC2=O)cc1
InChI
InChI=1S/C15H18O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13H,2-4,9H2,1H3,(H,17,18)
Molecular Formula
C15H18O3
HBD / HBA
1 / 3
Enlaces Rotables
4
Átomos Pesados
18
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
A prodrug NSAID that is converted to its active form in the body, used in Japan and other Asian countries to treat pain and inflammation from arthritis and musculoskeletal conditions. It may have a lower rate of gastrointestinal side effects than some other NSAIDs.
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Yes, Loxoprofen is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL19299. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3965. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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