Prodrug

Chemistry

A pharmacologically inactive compound that is metabolically converted to an active drug in vivo. Used to improve bioavailability, reduce toxicity, or target specific tissues.

Examples

Enalapril -> enalaprilat
Codeine -> morphine (CYP2D6)
Valacyclovir -> acyclovir

Did You Know?

A pharmacologically inactive compound that is metabolically converted to an active drug in vivo. Used to improve bioavailability, reduce toxicity, or target specific tissues.