Pegaptanib Sodium

CHEMBL1201421 Phase 4 Aprobado Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
g/mol
LogP
Phase
4

A sodium salt form of pegaptanib, an RNA aptamer that binds and inhibits vascular endothelial growth factor (VEGF-165), used to treat neovascular (wet) age-related macular degeneration. By blocking abnormal blood vessel growth in the retina, it helps preserve vision.

Áreas terapéuticas

Mecanismo de acción

Inhibits vascular endothelial growth factor (VEGF) signaling, blocking angiogenesis (new blood vessel formation) that tumors require for growth and metastasis.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mecanismo

Inhibits vascular endothelial growth factor (VEGF) signaling, blocking angiogenesis (new blood vessel formation) that tumors require for growth and metastasis.

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

A sodium salt form of pegaptanib, an RNA aptamer that binds and inhibits vascular endothelial growth factor (VEGF-165), used to treat neovascular (wet) age-related macular degeneration. By blocking abnormal blood vessel growth in the retina, it helps preserve vision.

Inhibits vascular endothelial growth factor (VEGF) signaling, blocking angiogenesis (new blood vessel formation) that tumors require for growth and metastasis.

Yes, Pegaptanib Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

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References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201421. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.