Potassium Oxybate
Potassium oxybate is the potassium salt form of gamma-hydroxybutyrate (GHB), a naturally occurring CNS depressant that acts on GABA-B receptors and specific GHB receptors in the brain to promote slow-wave sleep and reduce daytime sleepiness and cataplexy. It is used as an alternative formulation of sodium oxybate for the treatment of narcolepsy, particularly to reduce the sodium burden in patients with hypertension or sodium-restricted diets.
Peso molecular
142,1900 g/mol
TPSA
60,40 Ų
Áreas terapéuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estructura 2D
Cite this structure
Embed this structure
SMILES
O=C([O-])CCCO.[K+]
InChI
InChI=1S/C4H8O3.K/c5-3-1-2-4(6)7;/h5H,1-3H2,(H,6,7);/q;+1/p-1
Molecular Formula
C4H7KO3
HBD / HBA
1 / 3
Enlaces Rotables
3
Átomos Pesados
8
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
Potassium oxybate is the potassium salt form of gamma-hydroxybutyrate (GHB), a naturally occurring CNS depressant that acts on GABA-B receptors and specific GHB receptors in the brain to promote slow-wave sleep and reduce daytime sleepiness and cataplexy. It is used as an alternative formulation of sodium oxybate for the treatment of narcolepsy, particularly to reduce the sodium burden in patients with hypertension or sodium-restricted diets.
Yes, Potassium Oxybate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4594395. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 23689651. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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