Sarecycline
Sarecycline is a narrow-spectrum tetracycline-class antibiotic with anti-inflammatory properties, approved for the treatment of inflammatory lesions of non-nodular moderate-to-severe acne vulgaris. Unlike broad-spectrum tetracyclines, its narrow spectrum reduces disruption of gut microbiota while inhibiting bacterial protein synthesis via binding to the 30S ribosomal subunit. Investigational use in stroke has been proposed based on its matrix metalloproteinase inhibitory and anti-neuroinflammatory properties.
Peso molecular
487,5000 g/mol
LogP
1,10
TPSA
174,00 Ų
Regla de cinco de Lipinski
Cumple
Áreas terapéuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estructura 2D
Cite this structure
Embed this structure
SMILES
CON(C)Cc1ccc(O)c2c1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C1C2=O
InChI
InChI=1S/C24H29N3O8/c1-26(2)18-13-8-11-7-12-10(9-27(3)35-4)5-6-14(28)16(12)19(29)15(11)21(31)24(13,34)22(32)17(20(18)30)23(25)33/h5-6,11,13,18,28,30-31,34H,7-9H2,1-4H3,(H2,25,33)/t11-,13-,18-,24-/m0/s1
Molecular Formula
C24H29N3O8
HBD / HBA
5 / 10
Enlaces Rotables
5
Átomos Pesados
35
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Preguntas frecuentes
Sarecycline is a narrow-spectrum tetracycline-class antibiotic with anti-inflammatory properties, approved for the treatment of inflammatory lesions of non-nodular moderate-to-severe acne vulgaris. Unlike broad-spectrum tetracyclines, its narrow spectrum reduces disruption of gut microbiota while inhibiting bacterial protein synthesis via binding to the 30S ribosomal subunit. Investigational use in stroke has been proposed based on its matrix metalloproteinase inhibitory and anti-neuroinflammatory properties.
Yes, Sarecycline is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2364632. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 54681908. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="sarecycline"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/sarecycline/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/sarecycline/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/sarecycline/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="sarecycline"></drugfyi-drug>