Trospium Chloride

CHEMBL3084748 Phase 4 Aprobado Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
428.0 g/mol
LogP
Phase
4

Trospium chloride is the chloride salt form of trospium, a quaternary ammonium antimuscarinic used for overactive bladder syndrome by selectively blocking M3 muscarinic receptors in bladder smooth muscle. It reduces detrusor overactivity, decreasing urinary urgency, frequency, and incontinence episodes. The quaternary ammonium structure minimizes blood-brain barrier penetration, offering a favorable CNS safety profile.

Peso molecular

428,0000 g/mol

TPSA

46,50 Ų

Áreas terapéuticas

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estructura 2D

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SMILES

O=C(O[C@H]1C[C@H]2CC[C@@H](C1)[N+]21CCCC1)C(O)(c1ccccc1)c1ccccc1.[Cl-]

InChI

InChI=1S/C25H30NO3.ClH/c27-24(25(28,19-9-3-1-4-10-19)20-11-5-2-6-12-20)29-23-17-21-13-14-22(18-23)26(21)15-7-8-16-26;/h1-6,9-12,21-23,28H,7-8,13-18H2;1H/q+1;/p-1/t21-,22+,23+;

Molecular Formula

C25H30ClNO3

HBD / HBA

1 / 4

Enlaces Rotables

5

Átomos Pesados

30

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

Trospium chloride is the chloride salt form of trospium, a quaternary ammonium antimuscarinic used for overactive bladder syndrome by selectively blocking M3 muscarinic receptors in bladder smooth muscle. It reduces detrusor overactivity, decreasing urinary urgency, frequency, and incontinence episodes. The quaternary ammonium structure minimizes blood-brain barrier penetration, offering a favorable CNS safety profile.

Yes, Trospium Chloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3084748. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 5284631. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.