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Vaccinia Virus, Live Modified

CHEMBL6068373 Phase 4 Aprobado Vaccine component
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
— g/mol
LogP
—
Phase
4

Modified vaccinia Ankara (MVA) is a highly attenuated strain of vaccinia virus created by serial passage in chicken embryo fibroblasts, producing a replication-incompetent virus used as a vaccine vector and smallpox vaccine. It is used as the basis for JYNNEOS/Imvamune, approved for smallpox and monkeypox prevention, and as a vaccine vector platform for HIV, tuberculosis, malaria, and other infectious diseases. Its attenuated nature provides improved safety compared to traditional vaccinia while maintaining strong immunogenicity.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

Modified vaccinia Ankara (MVA) is a highly attenuated strain of vaccinia virus created by serial passage in chicken embryo fibroblasts, producing a replication-incompetent virus used as a vaccine vector and smallpox vaccine. It is used as the basis for JYNNEOS/Imvamune, approved for smallpox and monkeypox prevention, and as a vaccine vector platform for HIV, tuberculosis, malaria, and other infectious diseases. Its attenuated nature provides improved safety compared to traditional vaccinia while maintaining strong immunogenicity.

Yes, Vaccinia Virus, Live Modified is an approved drug. It has reached clinical phase 4. It is classified as a Vaccine component.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL6068373. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.