Vasopressin

CHEMBL373742 Phase 4 Aprobado Protein

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

— g/mol

LogP

—

Phase

4

Vasopressin (antidiuretic hormone, ADH) is an endogenous nonapeptide synthesized in the hypothalamus that acts on V1 receptors in vascular smooth muscle to cause vasoconstriction and on V2 receptors in renal collecting ducts to promote water reabsorption and urine concentration. Pharmacologically, it is used for vasodilatory shock (septic shock, post-cardiac surgery vasodilation) as a vasopressor and for diabetes insipidus due to ADH deficiency. Its vasopressor properties are exploited in resuscitation protocols and gastrointestinal bleeding.

Áreas terapéuticas

Cáncer colorrectal Cáncer de mama Cáncer de próstata Dolor crónico Enfermedad cardiovascular Enfermedad renal crónica Esquizofrenia Hepatitis C Hiperplasia prostática benigna Hipertensión Ictus Insuficiencia cardíaca Manejo del dolor Trastorno bipolar Trastorno de ansiedad generalizada Trastorno depresivo mayor Trombosis venosa profunda / Embolia pulmonar

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estructura 2D

SVG PNG

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SMILES

N=C(N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O

InChI

InChI=1S/C46H65N15O12S2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53)/t27-,28-,29-,30-,31-,32-,33-,34-/m0/s1

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Preguntas frecuentes

Vasopressin (antidiuretic hormone, ADH) is an endogenous nonapeptide synthesized in the hypothalamus that acts on V1 receptors in vascular smooth muscle to cause vasoconstriction and on V2 receptors in renal collecting ducts to promote water reabsorption and urine concentration. Pharmacologically, it is used for vasodilatory shock (septic shock, post-cardiac surgery vasodilation) as a vasopressor and for diabetes insipidus due to ADH deficiency. Its vasopressor properties are exploited in resuscitation protocols and gastrointestinal bleeding.

Yes, Vasopressin is an approved drug. It has reached clinical phase 4. It is classified as a Protein.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL373742. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

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Estructura

Datos Rápidos

Sinónimos: 2

Enlaces externos

ChEMBL CHEMBL373742

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Aviso médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.