Enterohepatic Recirculation

Pharmacokinetics

The process where a drug excreted in bile is reabsorbed from the intestine back into portal circulation. Creates secondary plasma peaks and prolongs apparent half-life.

Ejemplos

  • Oral contraceptives (antibiotic interaction)
  • Mycophenolate
  • Diclofenac

¿Sabías que...?

The process where a drug excreted in bile is reabsorbed from the intestine back into portal circulation. Creates secondary plasma peaks and prolongs apparent half-life.