Captopril vs Memantine

## Captopril vs Memantine: Overview

This comparison examines the pharmacological differences between **Captopril** and **Memantine**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Memantine**: Non-competitive NMDA receptor antagonist.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Memantine — 60-80 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Memantine — C12H21N.

**Molecular Weight**: Captopril — 217.2850 g/mol; Memantine — 179.3080 g/mol.

**Type**: Captopril — Small molecule; Memantine — Small molecule.