Dapagliflozin vs Metformin

## Dapagliflozin vs Metformin: Overview

This comparison examines the pharmacological differences between **Dapagliflozin** and **Metformin**.

## Mechanism of Action

**Dapagliflozin**: Selective SGLT2 inhibitor reducing renal glucose and sodium reabsorption.

**Metformin**: Activates AMP-activated protein kinase, decreasing hepatic glucose production.

## Pharmacokinetics

**Half-life**: Dapagliflozin — 12.9 hours; Metformin — 4-9 hours.

## Chemical Properties

**Molecular Formula**: Dapagliflozin — C21H25ClO6; Metformin — C4H11N5.

**Molecular Weight**: Dapagliflozin — 408.8730 g/mol; Metformin — 129.1640 g/mol.

**Type**: Dapagliflozin — Small molecule; Metformin — Small molecule.