Chlormadinone Acetate
A synthetic progestogen with additional antiandrogen activity used in oral contraceptives and to treat androgen-dependent conditions such as acne and hirsutism. It suppresses ovulation through inhibition of the hypothalamic-pituitary axis and alters cervical mucus. It is not approved in the United States but is widely used in Europe and other regions.
Masse moléculaire
404,9000 g/mol
LogP
3,60
TPSA
60,40 Ų
Règle des 5 de Lipinski
Conforme
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Structure 2D
Cite this structure
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SMILES
CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C=C(Cl)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C
InChI
InChI=1S/C23H29ClO4/c1-13(25)23(28-14(2)26)10-7-18-16-12-20(24)19-11-15(27)5-8-21(19,3)17(16)6-9-22(18,23)4/h11-12,16-18H,5-10H2,1-4H3/t16-,17+,18+,21-,22+,23+/m1/s1
Molecular Formula
C23H29ClO4
HBD / HBA
- / 4
Liaisons Rotatives
3
Atomes Lourds
28
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
A synthetic progestogen with additional antiandrogen activity used in oral contraceptives and to treat androgen-dependent conditions such as acne and hirsutism. It suppresses ovulation through inhibition of the hypothalamic-pituitary axis and alters cervical mucus. It is not approved in the United States but is widely used in Europe and other regions.
Yes, Chlormadinone Acetate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL110691. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 9324. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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