Chlormadinone Acetate
A synthetic progestogen with additional antiandrogen activity used in oral contraceptives and to treat androgen-dependent conditions such as acne and hirsutism. It suppresses ovulation through inhibition of the hypothalamic-pituitary axis and alters cervical mucus. It is not approved in the United States but is widely used in Europe and other regions.
Peso Molecular
404,9000 g/mol
LogP
3,60
TPSA
60,40 Ų
Regra dos 5 de Lipinski
Aprovado
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estrutura 2D
Cite this structure
Embed this structure
SMILES
CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C=C(Cl)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C
InChI
InChI=1S/C23H29ClO4/c1-13(25)23(28-14(2)26)10-7-18-16-12-20(24)19-11-15(27)5-8-21(19,3)17(16)6-9-22(18,23)4/h11-12,16-18H,5-10H2,1-4H3/t16-,17+,18+,21-,22+,23+/m1/s1
Molecular Formula
C23H29ClO4
HBD / HBA
- / 4
Ligações Rotacionáveis
3
Átomos Pesados
28
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
A synthetic progestogen with additional antiandrogen activity used in oral contraceptives and to treat androgen-dependent conditions such as acne and hirsutism. It suppresses ovulation through inhibition of the hypothalamic-pituitary axis and alters cervical mucus. It is not approved in the United States but is widely used in Europe and other regions.
Yes, Chlormadinone Acetate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL110691. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 9324. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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