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Esomeprazole Magnesium

CHEMBL5314366 Phase 4 Approuvé Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
713.1 g/mol
LogP
—
Phase
4

The magnesium salt form of esomeprazole, this proton pump inhibitor blocks acid production in the stomach to treat acid reflux and GERD. The magnesium salt helps with the formulation of delayed-release capsules.

Masse moléculaire

713,1000 g/mol

TPSA

163,00 Ų

Aires thérapeutiques

Asthma Gastroesophageal Reflux Disease

Mécanisme d'action

S-isomer of omeprazole; proton pump inhibitor irreversibly blocking gastric H+/K+-ATPase.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mécanisme

S-isomer of omeprazole; proton pump inhibitor irreversibly blocking gastric H+/K+-ATPase.

Structure 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
COc1ccc2[nH]c([S@@+]([O-])Cc3ncc(C)c(OC)c3C)nc2c1.COc1ccc2[nH]c([S@@+]([O-])Cc3ncc(C)c(OC)c3C)nc2c1.O.O.O.[Mg+2]

                

                

                
                

                    
InChI

                    
InChI=1S/2C17H19N3O3S.Mg.3H2O/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;;;;/h2*5-8H,9H2,1-4H3,(H,19,20);;3*1H2/q;;+2;;;/t2*24-;;;;/m00..../s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C34H36MgN6O6S2

                    

                    
                    

                        
HBD / HBA

                        
- / 14

                    

                    
                    

                        
Liaisons Rotatives

                        
10

                    

                    
                    
                    

                        
Atomes Lourds

                        
49

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Foire aux questions

                

                    
                    

                        
                        

                            
The magnesium salt form of esomeprazole, this proton pump inhibitor blocks acid production in the stomach to treat acid reflux and GERD. The magnesium salt helps with the formulation of delayed-release capsules.

                        

                    

                    

                    

                    
                    

                        
                        

                            
S-isomer of omeprazole; proton pump inhibitor irreversibly blocking gastric H+/K+-ATPase.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Esomeprazole Magnesium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL5314366.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 9568613.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Avertissement médical

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.