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Esomeprazole Magnesium

CHEMBL5314366 Phase 4 已批准 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
713.1 g/mol
LogP
—
Phase
4

The magnesium salt form of esomeprazole, this proton pump inhibitor blocks acid production in the stomach to treat acid reflux and GERD. The magnesium salt helps with the formulation of delayed-release capsules.

分子量

713.1000 g/mol

TPSA

163.00 Ų

治疗领域

Asthma Gastroesophageal Reflux Disease

作用机制

S-isomer of omeprazole; proton pump inhibitor irreversibly blocking gastric H+/K+-ATPase.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

机制

S-isomer of omeprazole; proton pump inhibitor irreversibly blocking gastric H+/K+-ATPase.

二维结构

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
COc1ccc2[nH]c([S@@+]([O-])Cc3ncc(C)c(OC)c3C)nc2c1.COc1ccc2[nH]c([S@@+]([O-])Cc3ncc(C)c(OC)c3C)nc2c1.O.O.O.[Mg+2]

                

                

                
                

                    
InChI

                    
InChI=1S/2C17H19N3O3S.Mg.3H2O/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;;;;/h2*5-8H,9H2,1-4H3,(H,19,20);;3*1H2/q;;+2;;;/t2*24-;;;;/m00..../s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C34H36MgN6O6S2

                    

                    
                    

                        
HBD / HBA

                        
- / 14

                    

                    
                    

                        
可旋转键数

                        
10

                    

                    
                    
                    

                        
重原子数

                        
49

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
常见问题

                

                    
                    

                        
                        

                            
The magnesium salt form of esomeprazole, this proton pump inhibitor blocks acid production in the stomach to treat acid reflux and GERD. The magnesium salt helps with the formulation of delayed-release capsules.

                        

                    

                    

                    

                    
                    

                        
                        

                            
S-isomer of omeprazole; proton pump inhibitor irreversibly blocking gastric H+/K+-ATPase.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Esomeprazole Magnesium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL5314366.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 9568613.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
医疗免责声明

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.