Fostemsavir Tromethamine

CHEMBL3301598 Phase 4 Approuvé Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

704.6 g/mol

LogP

—

Phase

4

This tromethamine salt form of fostemsavir is an attachment inhibitor that prevents HIV from binding to and entering human immune cells. It is used as part of combination antiretroviral therapy for adults with multidrug-resistant HIV who have limited treatment options.

Masse moléculaire

704,6000 g/mol

TPSA

269,00 Å²

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Structure 2D

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SMILES

COc1cnc(-n2cnc(C)n2)c2c1c(C(=O)C(=O)N1CCN(C(=O)c3ccccc3)CC1)cn2COP(=O)(O)O.NC(CO)(CO)CO

InChI

InChI=1S/C25H26N7O8P.C4H11NO3/c1-16-27-14-32(28-16)23-21-20(19(39-2)12-26-23)18(13-31(21)15-40-41(36,37)38)22(33)25(35)30-10-8-29(9-11-30)24(34)17-6-4-3-5-7-17;5-4(1-6,2-7)3-8/h3-7,12-14H,8-11,15H2,1-2H3,(H2,36,37,38);6-8H,1-3,5H2

Molecular Formula

C29H37N8O11P

HBD / HBA

6 / 15

Liaisons Rotatives

11

Atomes Lourds

49

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Foire aux questions

This tromethamine salt form of fostemsavir is an attachment inhibitor that prevents HIV from binding to and entering human immune cells. It is used as part of combination antiretroviral therapy for adults with multidrug-resistant HIV who have limited treatment options.

Yes, Fostemsavir Tromethamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3301598. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 46892186. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Données Clés

Formule: C29H37N8O11P
Synonymes: 1

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Avertissement médical

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.