Hydroxyurea
This oral chemotherapy drug works by inhibiting an enzyme called ribonucleotide reductase, slowing the growth of rapidly dividing cells. It is used to treat sickle cell disease (by increasing fetal hemoglobin), certain leukemias, and polycythemia vera. Regular blood count monitoring is essential during treatment.
Masse moléculaire
76,0550 g/mol
LogP
-1,80
TPSA
75,40 Ų
Règle des 5 de Lipinski
Conforme
Aires thérapeutiques
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Structure 2D
Cite this structure
Embed this structure
SMILES
NC(=O)NO
InChI
InChI=1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)
Molecular Formula
CH4N2O2
HBD / HBA
3 / 2
Liaisons Rotatives
0
Atomes Lourds
5
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
This oral chemotherapy drug works by inhibiting an enzyme called ribonucleotide reductase, slowing the growth of rapidly dividing cells. It is used to treat sickle cell disease (by increasing fetal hemoglobin), certain leukemias, and polycythemia vera. Regular blood count monitoring is essential during treatment.
Yes, Hydroxyurea is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL467. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3657. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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